Biliary atresia

Effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition in experimental biliary atresia mouse models

J. Y. Wang, Li, Z. H., Ye, M., Feng, Q., Chen, Z. M., Ye, X. S., Wu, Z. G., Wang, B., Liu, L., Yao, J., Wang, J. Y., Li, Z. H., Ye, M., Feng, Q., Chen, Z. M., Ye, X. S., Wu, Z. G., Wang, B., Liu, L., and Yao, J., Effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition in experimental biliary atresia mouse models, vol. 15, p. -, 2016.

Biliary atresia (BA) is a destructive bile duct disease occurring in newborn children within a few weeks after birth. In this study, the effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition (EMT) in experimental BA was explored by constructing BA mouse models via Rhesus rotavirus vaccine infection. miR-29c and miR-129-5p expression was analyzed by real-time quantitative polymerase chain reaction. EMT was established by induction with transforming growth factor (TGF)-β1.

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