Beclin-1

Association of Beclin-1 and microRNA-30a expression with the severity and treatment response of colorectal cancer

L. Liu, Meng, T., Wang, Q. S., Jin, H. Z., Sun, Z. Q., Jin, B., Fang, F., Wang, H. J., Liu, L., Meng, T., Wang, Q. S., Jin, H. Z., Sun, Z. Q., Jin, B., Fang, F., Wang, H. J., Liu, L., Meng, T., Wang, Q. S., Jin, H. Z., Sun, Z. Q., Jin, B., Fang, F., and Wang, H. J., Association of Beclin-1 and microRNA-30a expression with the severity and treatment response of colorectal cancer, vol. 15, p. -, 2016.

We investigated the associations between Beclin-1 and microRNA-30a (miR-30a) expression and the severity and treatment response in colorectal cancer (CRC). Our sample size consisted of 139 CRC patients who were treated with surgery alone. Immunohistochemistry was used to investigate the expression and prognostic significance of Beclin-1 in CRC, while the weak expression of Beclin-1 in normal tissue was used as the basis for assessing tumors (control group). Real-time reverse transcription-polymerase chain reaction quantified miR-30a levels.

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