Azoospermia

Copy number variations in spermatogenic failure patients with chromosomal abnormalities and unexplained azoospermia

Y. Dong, Pan, Y., Wang, R., Zhang, Z., Xi, Q., and Liu, R. - Z., Copy number variations in spermatogenic failure patients with chromosomal abnormalities and unexplained azoospermia, vol. 14, pp. 16041-16049, 2015.

Male infertility is mostly caused by spermatogenic failure. Currently, routine genetic analyses of unexplained azoospermia or oligozoospermia are limited to the investigation of Y chromosomal microdeletions and chromosome karyotype analyses. The aim of this study was to find spermatogenic failure genes in patients with chromosomal abnormalities and unexplained azoospermia caused by copy number variations in order to provide a theoretical basis for further research.

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