ATP1A1

Polymorphisms of the ATP1A1 gene associated with mastitis in dairy cattle

Y. X. Liu, Xu, C. H., Gao, T. Y., and Sun, Y., Polymorphisms of the ATP1A1 gene associated with mastitis in dairy cattle, vol. 11, pp. 651-660, 2012.

Mastitis affects the concentrations of potassium and sodium in milk. Since sodium-potassium adenosine triphosphatase (Na+, K+-ATPase) is critical for maintaining the homeostasis of these two ions, and is involved in cell apoptosis and pathogenesis, we presumed that polymorphism of the ATP1A1 gene, which encodes the bovine Na+, K+-ATPase α1 subunit could be associated with mastitis.

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