ATP-binding cassette

Effect of variation of ABCB1 and GSTP1 on osteosarcoma survival after chemotherapy

J. Z. Li, Tian, Z. Q., Jiang, S. N., and Feng, T., Effect of variation of ABCB1 and GSTP1 on osteosarcoma survival after chemotherapy, vol. 13, pp. 3186-3192, 2014.

We conducted a comprehensive study to investigate the role of genes involved in metabolic and transport pathways in response to chemotherapy and clinical outcome of osteosarcoma patients. Genotyping of seven gene polymorphisms was performed on a 384-well plate format on the Sequenom MassARRAY platform in 162 patients with osteosarcoma. We studied the correlation of the seven gene polymorphisms with response to chemotherapy and clinical outcome of patients.

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