Atopic asthma

Association of CD14 C159T polymorphism with atopic asthma susceptibility in children from Southeastern China: a case-control study

Y. N. Zhang, Li, Y. J., Li, H., Zhou, H., and Shao, X. J., Association of CD14 C159T polymorphism with atopic asthma susceptibility in children from Southeastern China: a case-control study, vol. 14, pp. 4311-4317, 2015.

CD14 is involved in primary immune and inflammatory responses. The -159 C/T variation in the CD14 gene plays an important role in regulating CD14 expression and has been associated with the susceptibility to various diseases, including allergies. In this study, we examined the association between the C-159T polymorphism and atopic asthma susceptibility in children from Southeastern China. The study population included 746 unrelated children of Chinese Han nationality (362 patients with atopic asthma and 384 healthy controls).

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