Association analysis

A 425 T>C polymorphism in complement C7 association with resistance to Aeromonas hydrophila in grass carp

Y. B. Shen, Zhang, J. B., Fu, J. J., Xu, X. Y., Li, J. L., Wang, R. Q., Xuan, Y. F., Shen, Y. B., Zhang, J. B., Fu, J. J., Xu, X. Y., Li, J. L., Wang, R. Q., Xuan, Y. F., Shen, Y. B., Zhang, J. B., Fu, J. J., Xu, X. Y., Li, J. L., Wang, R. Q., and Xuan, Y. F., A 425 T>C polymorphism in complement C7 association with resistance to Aeromonas hydrophila in grass carp, vol. 15, p. -, 2016.

Aeromonas hydrophila, a widespread bacterium in the aquatic environment, causes hemorrhagic septicemia in fish. In the last decade, the disease has caused mass mortalities and tremendous economic loss in cultured fish. The complement component C7 is a terminal component of complement that interacts in a sequence of polymerization reactions with other terminal complement components to form a membrane attack complex. The formation of the membrane attack complex creates a pore in the membranes of certain pathogen that can lead to their death.

Association of the LMNA gene single nucleotide polymorphism rs4641 with bdilated cardiomyopathy

J. Yin, Yang, J., Ren, F. X., Sun, C. M., Li, L. D., Han, L. Y., Cai, S. L., Zhang, C. H., Zhang, Z. Q., Zhang, Z. T., and Wang, H., Association of the LMNA gene single nucleotide polymorphism rs4641 with bdilated cardiomyopathy, vol. 14, pp. 15427-15434, 2015.

Recently, studies on the pathogenesis of dilated cardiomyopathy (DCM) have focused on the underlying molecular biology and the association between single nucleotide polymorphisms (SNPs) and disease. This study was designed to explore the association between the rs4641 SNP of the LMNA gene and DCM in order to identify a new gene locus related to DCM. Polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing were employed to detect and genotype rs4641 in 198 patients with DCM and 160 healthy controls.

Characterization of microsatellite markers and their correlations with growth traits in Mandarin fish (Siniperca chuatsi)

T. L. Yi, Fang, L., Liang, X. F., Sun, L. F., Li, J., Luo, X. N., Guo, W. J., Dou, Y. Q., and Sun, J., Characterization of microsatellite markers and their correlations with growth traits in Mandarin fish (Siniperca chuatsi), vol. 14, pp. 8926-8934, 2015.

Mandarin fish (Siniperca chuatsi) is a traditionally cultured freshwater fish with high commercial value in China. To facilitate marker-assisted selection for genetic improvement of this species, 100 microsatellite markers identified in previous studies were characterized in the 25 largest and 25 smallest individuals. Twenty polymorphic loci were used to genotype 200 individuals, and the associations between their genotypes and growth traits were examined.

Subscribe to Association analysis