Protective effect of the polarity of macrophages regulated by IL-37 on atherosclerosis
“Protective effect of the polarity of macrophages regulated by IL-37 on atherosclerosis”, vol. 15, p. -, 2016.
, As an anti-inflammatory cytokine, interleukin-37 (IL-37) provides certain protective effects against inflammatory and autoimmune diseases. Recent reports indicate that IL-37 is expressed in foam cells of atherosclerotic plaques in both the coronary and carotid arteries of humans, suggesting the possible involvement of IL-37 in the pathogenesis and progression of atherosclerosis. Current evidence supports the protective role that IL-37 plays against atherosclerosis via the regulation of different subtypes of macrophage.