Arg399Gln

Investigation of the role of XRCC1 genetic polymorphisms in the development of gliomas in a Chinese population

S. C. Fan, Zhou, J. G., Yin, J. Z., Fan, S. C., Zhou, J. G., and Yin, J. Z., Investigation of the role of XRCC1 genetic polymorphisms in the development of gliomas in a Chinese population, vol. 15, p. -, 2016.

We conducted a study in a Chinese Han population to investigate the role of XRCC1 gene polymorphisms (Arg399Gln and Arg194Trp) with a risk of susceptibility to gliomas. Samples from 115 patients with gliomas and 228 control subjects were consecutively collected between March 2012 and December 2014. Genotype analysis of XRCC1 Arg399Gln and Arg194Trp was performed using polymerase chain reaction-restriction fragment length polymorphism assay. All the analyses were performed using the SPSS 17.0 software package.

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