Apoptosis

Effect and mechanism of miR-126 in myocardial ischemia reperfusion

B. Li, Tao, Y., and Huang, Q., Effect and mechanism of miR-126 in myocardial ischemia reperfusion, vol. 14, pp. 18990-18998, 2015.

Multiple studies have shown microRNAs to play an important role in disease occurrence and development. The role of miRNAs in ischemia-reperfusion injury, however, requires further investigation and the aim of this study was therefore to assess miR-126 expression in myocardial ischemia reperfusion and the effects of miR-126 on myocardial ischemia-reperfusion injury. An in vitro model of ischemia-reperfusion injury was established using rat myocardial H9c2 cells and miR-126 expression in these cells was assessed by real-time PCR.

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