Roles of osteocyte apoptosis in steroid-induced avascular necrosis of the femoral head
“Roles of osteocyte apoptosis in steroid-induced avascular necrosis of the femoral head”, vol. 15, p. -, 2016.
, An animal model of steroid-induced avascular necrosis of the femoral head (SANFH) was established to investigate the roles of osteocyte apoptosis in this process. Forty five-month-old male and female Japanese white rabbits were randomly divided into groups A (hormone + endotoxin), B (hormone alone), C (endotoxin alone), and D (blank control). Animals were sacrificed two and four weeks following the final treatment (N = 5 for each group at each time point). Bilateral femoral heads were fixed and decalcified, and empty lacunae were counted by hematoxylin staining.