Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway
“Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway”, vol. 15, p. -, 2016.
, Paclitaxel (PTX) is a mitotic inhibitor widely used in chemotherapy for many types of cancers, including solid tumors and hematological malignancies. However, the molecular basis of the anti-proliferation activity of PTX is not fully understood. In this paper, we focused on the role of c-Jun N-terminal kinase (JNK) pathways in PTX-induced apoptosis and proliferation inhibition.