Apoptosis

Aquaporin in the proliferation and apoptosis of diabetic myocardial cells

P. F. Zhao and Sun, M. J., Aquaporin in the proliferation and apoptosis of diabetic myocardial cells, vol. 14, pp. 17366-17372, 2015.

The aim of this study was to explore the effect of aquaporin on the molecular mechanism of human diabetic myocardial cell apoptosis. The methylthiazolyle tetrazolium assay was used to detect the inhibitory effect of different concentrations of aquaporin on cell growth. The rate of aquaporin-induced myocardial cell apoptosis was detected by flow cytometric analysis of Annexin V-fluorescein isothiocyanate/propidium iodide double-stained cells. We also attempted to quantify the expression of Bcl-2, Bax, caspase-3, and survivin in diabetic myocardial cells by western blot analysis.

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