Apolipoprotein B

Serum lipid abnormalities are not associated with apoB 3' VNTR polymorphism in nephrotic children

P. Hu, Hu, B., Qin, Y. H., Lu, L., Li, Z. Q., Tao, L. Q., Pei, Q., and Chen, J., Serum lipid abnormalities are not associated with apoB 3' VNTR polymorphism in nephrotic children, vol. 12, pp. 765-774, 2013.

Apolipoprotein B (apoB) gene 3' variable number of tandem repeat (VNTR) is highly variable, and therefore can be an informative marker for associative analysis of lipid metabolism. This is the first report focusing on a possible association of apoB VNTR polymorphism with nephrotic hyperlipidemia. Genomic DNA was extracted from 500 children with primary nephrotic syndrome (PNS) and 500 healthy controls. The apoB genotype was determined by PCR analysis.

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