APOA5/A4/C3/A1 gene cluster

Relationship of the APOA5/A4/C3/A1 gene cluster and APOB gene polymorphisms with dyslipidemia

H. J. Ou, Huang, G., Liu, W., Ma, X. L., Wei, Y., Zhou, T., and Pan, Z. M., Relationship of the APOA5/A4/C3/A1 gene cluster and APOB gene polymorphisms with dyslipidemia, vol. 14, pp. 9277-9290, 2015.

We determined the alleles of ten single nucleotide poly­morphisms (SNPs) in the APOA5/A4/C3/A1 gene cluster and in APOB in Han Chinese from Xinjiang Shihezi, China using MALDI-TOF mass spectrometry, and explored the correlation between these SNPs and dyslipidemia through a case-control study design with 250 pa­tients and 250 normal controls. All SNPs except for APOA5 rs2072560 conformed to Hardy-Weinberg equilibrium (all P > 0.05).

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