APC

Male-specific association of the APC rs383830 T allele with the risk of coronary heart disease

J. Y. Zhong, Zheng, X. W., Ye, H. D., Cui, H. B., Du, W. P., Zhang, Z. X., Fei, X. H., Lin, S. Y., Wang, J., Su, J., Chen, X. M., and Duan, S. W., “Male-specific association of the APC rs383830 T allele with the risk of coronary heart disease”, vol. 14, pp. 11745-11751, 2015.

APC is a tumor suppressor gene that is involved in the processes of cell migration and adhesion, transcriptional activation, and apoptosis. The goal of this study was to evaluate the contribution of the APC rs383830 polymorphism to coronary heart disease (CHD) in Han Chinese. A total of 783 patients with CHD and 737 controls were tested in the current association study.

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