Antibacterial activity

Antimicrobial activity of fermented Theobroma cacao pod husk extract

R. X. Santos, Oliveira, D. A., Sodré, G. A., Gosmann, G., Brendel, M., and Pungartnik, C., Antimicrobial activity of fermented Theobroma cacao pod husk extract, vol. 13, pp. 7725-7735, 2014.

Theobroma cacao L. contains more than 500 different chemical compounds some of which have been traditionally used for their antioxidant, anti-carcinogenic, immunomodulatory, vasodilatory, analgesic, and antimicrobial activities. Spontaneous aerobic fermentation of cacao husks yields a crude husk extract (CHE) with antimicrobial activity. CHE was fractioned by solvent partition with polar solvent extraction or by silica gel chromatography and a total of 12 sub-fractions were analyzed for chemical composition and bioactivity.

Antimicrobial activity and cytotoxicity of endophytes from Scapania verrucosa Heeg.

J. - G. Wu, Peng, W., Zeng, P. - Y., Wu, Y. - B., Yi, J., and Wu, J. - Z., Antimicrobial activity and cytotoxicity of endophytes from Scapania verrucosa Heeg., vol. 12, pp. 916-924, 2013.

We evaluated the antibacterial activity and cytotoxicity of endophytes isolated from Scapania verrucosa Heeg., which belongs to the liverwort class. A total of 49 endophytic fungi were isolated from S. verrucosa and classified into seven genera and one family in our previous study. In this study, the cytotoxic activity of the endophytes was assessed using the brine shrimp lethality bioassay, seven of which showed potent toxicity against the brine shrimp with 50% lethal concentration values less than 20 μg/mL.

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