Angiogenesis

Correlation between expression and significance of δ-catenin, CD31, and VEGF of non-small cell lung cancer

X. L. Liu, Liu, L. D., Zhang, S. G., Dai, S. D., Li, W. Y., and Zhang, L., Correlation between expression and significance of δ-catenin, CD31, and VEGF of non-small cell lung cancer, vol. 14, pp. 13496-13503, 2015.

We analyzed the expression and clinical significance of δ-catenin in non-small cell lung cancer (NSCLC) and investigated prognosis using human lung cancer samples. Eighty-nine NSCLC patients underwent operation between January and March 2009. There were 53 cases of squamous cell carcinoma, 31 adenocarcinoma, and 5 large cell carcinoma. δ-Catenin in NSCLC patients was detected by immunohistochemistry and analyzed in combination with the clinicopathological characteristics of lung cancer.

Effect of TIMP1 transfection on PTEN expression in human kidney proximal tubular cells

J. X. Chen, Cai, G. Y., Chen, X. M., Liu, H., Chen, X., Peng, Y. M., Liu, F. Y., Li, Z., and Shi, S. Z., Effect of TIMP1 transfection on PTEN expression in human kidney proximal tubular cells, vol. 14, pp. 17373-17383, 2015.

To explore the role of metalloproteinase-1 (TIMP-1) tissue inhibitor in the mechanisms of kidney aging, we observed the effects of sense and antisense transfection of TIMP-1 and of metalloproteinase (MMP) inhibitors on phosphatase and tensin homolog (PTEN), vascular endothelial growth factor (VEGF), and Flk-1 expression in TIMP-1 transgenic human proximal tubular epithelial cells (HKCs). Transfected HKCs were co-incubated with 100 μM MMP-2 and MMP-9 inhibitor III for 24 h to affect enzyme inhibition.

Subscribe to Angiogenesis