Ancestry informative markers

Self-declared ethnicity and genomic ancestry in prostate cancer patients from Brazil

J. S. Oliveira, Ferreira, R. S., Santos, L. M., Marin, L. J., Corrêa, R. X., Luizon, M. R., Simões, A. L., Gadelha, S. R., and Sousa, S. M. B., “Self-declared ethnicity and genomic ancestry in prostate cancer patients from Brazil”, vol. 15, no. 4, p. -, 2016.

INTRODUCTION

A rapid screening of ancestry for genetic association studies in an admixed population from Pernambuco, Brazil

A. V. C. Coelho, Moura, R. R., Cavalcanti, C. A. J., Guimarães, R. L., Sandrin-Garcia, P., Crovella, S., and Brandão, L. A. C., “A rapid screening of ancestry for genetic association studies in an admixed population from Pernambuco, Brazil”, vol. 14, pp. 2876-2884, 2015.

Genetic association studies determine how genes influence traits. However, non-detected population substructure may bias the analysis, resulting in spurious results. One method to detect substructure is to genotype ancestry informative markers (AIMs) besides the candidate variants, quantifying how much ancestral populations contribute to the samples’ genetic background. The present study aimed to use a minimum quantity of markers, while retaining full potential to estimate ancestries.

Subscribe to Ancestry informative markers