Amino acid sequence

Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5

L. Van Nieuwenhove, Rogé, S., Lejon, V., Guisez, Y., and Büscher, P., Characterization of Trypanosoma brucei gambiense variant surface glycoprotein LiTat 1.5, vol. 11. pp. 1260-1265, 2012.

At present, all available diagnostic antibody detection tests for Trypanosoma brucei gambiense human African trypanosomiasis are based on predominant variant surface glycoproteins (VSGs), such as VSG LiTat 1.5. During investigations aiming at replacement of the native VSGs by recombinant proteins or synthetic peptides, the sequence of VSG LiTat 1.5 was derived from cDNA and direct N-terminal amino acid sequencing.

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