Amino acid

Effect of high-concentrate diet on amino acid transporter expression and milk quality in Holstein dairy cows

Z. L. Xie, Ye, P. S., Zhang, Y. S., and Shen, X. Z., Effect of high-concentrate diet on amino acid transporter expression and milk quality in Holstein dairy cows, vol. 14, pp. 5246-5257, 2015.

In order to evaluate the effect of high-concentrate diet supplementation on milk protein content, six Holstein dairy cows were assigned into high-concentrate diet (HC) or low-concentrate diet (LC) groups (N = 3/group) for 50 days. With regard to milk protein, HC feeding significantly reduced the percentage of milk protein (P

In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi

A. C. R. Guimarães, Otto, T. D., Alves-Ferreira, M., Miranda, A. B., and Degrave, W. M., In silico reconstruction of the amino acid metabolic pathways of Trypanosoma cruzi, vol. 7, pp. 872-882, 2008.

Trypanosoma cruzi is the epidemiological agent of Chagas’ disease, affecting most of Central and South America, constituting a significant health and socio-economic problem. The parasite has a metabolism largely based on the consumption of amino acids, which participate in a diversity of metabolic pathways, leading to many crucial compounds for the survival of this parasite. Study of its enzymes has the potential to disclose new therapeutic targets and foster the development of new drugs.

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