Airway remodeling

Expression of M3 acetylcholine receptor in asthmatic mice and bronchial airway remodeling prediction

F. Zhao, Yang, J., Chen, P., Wang, Y., Zhang, H., Zhang, Q., Zhao, F., Yang, J., Chen, P., Wang, Y., Zhang, H., and Zhang, Q., Expression of M3 acetylcholine receptor in asthmatic mice and bronchial airway remodeling prediction, vol. 15, p. -, 2016.

This study aimed to investigate the role of M3 acetylcholine receptor (M3-AChR) expression in airway remodeling. Additionally, we aimed to evaluate the effects of ipratropium bromide solution inhaled in an early phase of asthma on airway remodeling in ovalbumin (OVA)-sensitized and challenged mice. Thirty BALB/c mice were divided into three groups, namely, control group (saline sensitized/challenged mice), asthma group (OVA sensitized/challenged mice), and treatment group (OVA sensitized/challenged mice treated by ipratropium bromide).

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