Adolescent

Association of PTPN22 gene polymorphism with type 1 diabetes mellitus in Chinese children and adolescents

H. W. Liu, Xu, R. Y., Sun, R. P., Wang, Q., Liu, J. L., Ge, W., and Yu, Z., Association of PTPN22 gene polymorphism with type 1 diabetes mellitus in Chinese children and adolescents, vol. 14, pp. 63-68, 2015.

Previous studies have indicated that the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22) is associated with type 1 diabetes (T1DM) in the Caucasian population. In the present study, we investigated the relationship between PTPN22 genetic polymorphisms and T1DM in Chinese children. A total of 202 children and adolescents with T1DM and 240 healthy control subjects of Chinese Han origin were included in our analysis.

Influence of aberrant myeloid expression on acute lymphoblastic leukemia in children and adolescents from Maranhão, Brazil

T. C. Lopes, Andrade, K. N. S., Camelo, N. L., Rodrigues, V. P., and Oliveira, R. A. G., Influence of aberrant myeloid expression on acute lymphoblastic leukemia in children and adolescents from Maranhão, Brazil, vol. 13, pp. 10301-10307, 2014.

The aim of this study was to evaluate myeloid expression in acute lymphoblastic leukemia (ALL) in children and adolescents who had been referred to the Oncology Department in a hospital in the State of Maranhão based on demographic, laboratory, and clinical data. Myeloid expression was evaluated in 65 patients under 18 years of age who were diagnosed with morphological, cytochemical, and immunophenotypes of ALL. Demographic, laboratory (hemogram), and clinical variables were obtained from medical records.

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