Acute myocardial infarction

Effect of hydroxy safflower yellow A on myocardial apoptosis after acute myocardial infarction in rats

M. X. Zhou, Fu, J. H., Zhang, Q., and Wang, J. Q., Effect of hydroxy safflower yellow A on myocardial apoptosis after acute myocardial infarction in rats, vol. 14, pp. 3133-3141, 2015.

This study aimed to investigate the effect of hydroxy safflower yellow A (HSYA) on myocardial apoptosis after acute myocardial infarction (AMI) in rats. We randomly divided 170 male Wistar rats into 6 groups (N = 23): normal control, sham, control, SY (90 mg/kg), HSYA high-dose (HSYA-H, 40 mg/kg), and HSYA low-dose groups (HSYA-L, 20 mg/kg). Myocardial ischemic injury was induced by ligating the anterior descending coronary artery, and the degree of myocardial ischemia was evaluated using electrocardiography and nitroblue tetrazolium staining.

Analysis and clinical significance of microRNA-499 expression levels in serum of patients with acute myocardial infarction

C. H. Zhao, Cheng, G. - C., He, R. L., Hong, Y., Wan, Q. L., Wang, Z. - Z., and Pan, Z. - Y., Analysis and clinical significance of microRNA-499 expression levels in serum of patients with acute myocardial infarction, vol. 14, pp. 4027-4034, 2015.

The aim of this study was to investigate the expression level of microRNA-499 and its clinical significance in serum of patients with acute myocardial infarction (AMI). We recruited 59 patients with AMI and 60 healthy individuals undergoing physical examination in our hospital during the same period as controls. Peripheral blood was drawn in the morning on the same day of microRNA extraction. The expression level of microRNA-499 was analyzed by real-time fluorescent quantitative polymerase chain reaction (qPCR).

High-sensitivity cardiac troponin T is a predictor of recurrent acute coronary syndrome in patients with acute myocardial infarction

S. - C. Sheng, Lu, X. - M., Kang, Y., Du, Y. - P., and Wang, G. - X., High-sensitivity cardiac troponin T is a predictor of recurrent acute coronary syndrome in patients with acute myocardial infarction, vol. 13, pp. 3819-3825, 2014.

High-sensitivity cardiac troponin T is a useful tool for diagnosing myocardial ischemia. However, its role in the prognosis of patients with acute myocardial infarction has not been studied. Here, the prognostic value of high-sensitivity cardiac troponin T for patients with acute myocardial infarction was investigated.

Intra-aortic balloon pump treatment for patients with acute anterior wall myocardial infarction after reperfusion therapy

C. G. Feng, Yang, X. J., Fu, Q., Wang, Y. J., Ruan, H. Y., Lu, Y., Li, X. L., and Zhang, X. P., Intra-aortic balloon pump treatment for patients with acute anterior wall myocardial infarction after reperfusion therapy, vol. 13, pp. 4280-4288, 2014.

We evaluated the effects of an intra-aortic balloon pump on hemodynamics, brain natriuretic peptide concentration and cardiac function of patients with acute myocardial infarction, after reperfusion therapy. Sixty-three patients with acute anterior wall ST-elevation myocardial infarction who underwent primary percutaneous coronary intervention were given an intra-aortic balloon pump (32 cases) or not (control group, 31 cases). The mean pulmonary arterial pressure, pulmonary capillary wedge pressure and cardiac index were measured with a Swan-Ganz catheter.

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