ACE2

Relationship between renal injury and the antagonistic roles of angiotensin-converting enzyme (ACE) and ACE2

C. Ma, Xin, H., Jiang, X. - Y., Wang, Y. - X., and Zhang, Y. - S., Relationship between renal injury and the antagonistic roles of angiotensin-converting enzyme (ACE) and ACE2, vol. 13, pp. 2333-2342, 2014.

Angiotensin-converting enzyme 2 (ACE2), a newly discovered carboxypeptidase in the renin-angiotensin system (RAS), antagonizes ACE activity and plays an active role during tissue injury. Yet the mechanism of its action is not well known. Using a streptozotocin (STZ)-induced renal injury rat model, we investigated the relationship between renal injury and the antagonism between ACE and ACE2.

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