3-NPA

Protective effect of proanthocyanidin against oxidative ovarian damage induced by 3-nitropropionic acid in mice

J. Q. Zhang, Xing, B. S., Zhu, C. C., Shen, M., Yu, F. X., and Liu, H. L., Protective effect of proanthocyanidin against oxidative ovarian damage induced by 3-nitropropionic acid in mice, vol. 14, pp. 2484-2494, 2015.

Oxidative stress, which poses a threat to reproductive health, causes many serious female reproductive diseases. In this study, we investigated whether proanthocyanidins (PC) have a protective effect against oxidative stress-induced ovarian damage. Forty female ICR mice were randomized into 4 groups: a control group, a control plus PC group, a 3-nitropropionic acid (3-NPA) group, and a 3-NPA plus PC group. An ovarian oxidative stress model induced by 3-NPA was constructed using female ICR mice.

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