[131I]-Herceptin

Visualization and body distribution of [131I]-herceptin in nude mice with BT-474 breast carcinoma

Z. X. Yang, Cao, H., Xing, C. G., Wei, S. H., Jiang, G. Q., and Liu, Z. L., Visualization and body distribution of [131I]-herceptin in nude mice with BT-474 breast carcinoma, vol. 13, pp. 6804-6812, 2014.

The study aimed to investigate the bio-distribution and radio-immuno-imaging features of [131I]-herceptin in nude mice with BT-474 breast carcinoma. [131I]-Herceptin was administrated by tail intravenous injection to the nude mice with BT-474 breast carcinoma. Radiocounting was performed at 4, 12, 24, 48, and 96 h after administration. The activity ratio in the tumor tissue and non-tumor tissue (T/NT) and the radiocounting percentage per gram tissue to the injected dose (%ID/g) were calculated.

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