11β-hydroxysteroid dehydrogenase type 1

11β-hydroxysteroid dehydrogenase type 1 gene expression is increased in ascending aorta tissue of metabolic syndrome patients with coronary artery disease

F. Atalar, Vural, B., Ciftci, C., Demirkan, A., Akan, G., Susleyici-Duman, B., Gunay, D., Akpinar, B., Sagbas, E., Ozbek, U., and Buyukdevrim, A. S., 11β-hydroxysteroid dehydrogenase type 1 gene expression is increased in ascending aorta tissue of metabolic syndrome patients with coronary artery disease, vol. 11, pp. 3122-3132, 2012.

11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) activity and mRNA levels are increased in visceral and subcutaneous adipose tissues of metabolic syndrome subjects. We analyzed 11β-HSD-1 expression in human epicardial adipose (EA) and ascending aorta (AA) tissues of metabolic syndrome patients and examined their contribution to the development of coronary atherosclerosis.

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