A RARE CASE STUDY: A MULTIPLE MYXOMAS INVOLVING BOTH RIGHT AND LEFT VENTRICLES IN NEONATE

Abstract

Cardiac myxomas are rare, with multiple myxomas even rarer (0.001%–0.03% incidence). They primarily arise in the left atrium (75%), with 20% in the right atrium, and less than 5% in the ventricles. Multiple ventricular myxomas without atrial involvement is extremely rare. Myxomas are mostly benign, and advances in imaging have made them more manageable. This case discusses a neonate with multiple myxomas in both ventricles. A 29-week preterm neonate, post-C-section, was admitted to the NICU with signs of pneumonia. Routine echocardiography revealed multiple masses in both ventricles. The right ventricle had five masses (ranging from 0.3–1.49 cm), and the left ventricle had three masses (ranging from 0.2–0.7 cm). Cardiac myxomas are commonly atrial. Atrial myxomas causing obstruction, thromboembolisms, and constitutional symptoms, while ventricular ones may cause chest pain, palpitations, or syncope. Diagnosis is made via histopathology and echocardiography. This patient presented with multiple mobile myxomas in both ventricles. Cardiac myxomas are rare tumors, with low incidence, typically affecting atrium, while multiple myxomas involving both ventricles are rare. This case describes a premature neonate diagnosed with multiple myxomas in both ventricles, exhibiting mild respiratory distress that improved with CPAP. Despite the presence of the tumors, there were no significant symptoms. Surgical resection is the standard treatment, with a low mortality rate and favorable recovery. Early detection via imaging and surgical intervention are crucial for optimal outcomes.