Association of polymorphisms of physiological candidate genes with phenotype and estimated breeding values of reproductive and growth traits in Thai indigenous chickens
Signal transducers and activators of transcription (STAT5B), dopamine receptors D2 (DRD2), bone morphogenetic protein (BMP15), and melatonin receptors type C (MTNR1C) play an important role in growth and reproductive traits in chickens. We studied the 9th generation of 93 Pradu Hang Dam and 95 Chee chickens examining PCR-restriction fragment length polymorphisms to genotype for growth and reproductive traits. There was no significant association between other traits, but we confirmed that in Pradu Hang Dam, DRD2 was associated with egg weight at the age at first egg while BMP15 was associated with egg weight at 300 days and body weight at 300 days. Moreover, MTNR1C was associated with egg weight at 300 days and egg number at 300 days. In Chee, MTNR1C was associated with egg number at 300 days. We suggest that DRD2, BMP15, and MTNR1C be used to select for early maturity and growth, while MTNR1C be used for egg number in Pradu Hang Dam. In Chee, MTNR1C can be a marker to improve egg production. For improving the egg production in Thai native chickens, we recommend that MTNR1C be used in marker-assisted selection.