Research Article

Investigation of TG gene variants and their effects on growth, carcass composition, and meat quality traits in Chinese steers

Published: May 22, 2015
Genet. Mol. Res. 14 (2) : 5320-5326 DOI: 10.4238/2015.May.22.2

Abstract

Thyroid hormones play an important role in regulating metabolism and can affect metabolism-related traits such as fat deposition. The thyroglobulin (TG) gene produces the precursor of thyroid hormones and has been proposed as a candidate gene for a quantitative trait locus with an effect on fat deposition. In this study, we identified 4 novel single nucleotide polymorphisms (SNPs) in the 5' flanking region of the TG gene using a DNA sequencing method. The SNP marker association analysis indicated that the T1355C SNPs were significantly associated with meat percentage (P TG gene-specific SNPs may be a useful marker for growth traits in marker-assisted selection programs in beef cattle.

Thyroid hormones play an important role in regulating metabolism and can affect metabolism-related traits such as fat deposition. The thyroglobulin (TG) gene produces the precursor of thyroid hormones and has been proposed as a candidate gene for a quantitative trait locus with an effect on fat deposition. In this study, we identified 4 novel single nucleotide polymorphisms (SNPs) in the 5' flanking region of the TG gene using a DNA sequencing method. The SNP marker association analysis indicated that the T1355C SNPs were significantly associated with meat percentage (P TG gene-specific SNPs may be a useful marker for growth traits in marker-assisted selection programs in beef cattle.